Phenothiazine. Allergies; antiemetic; sedation; premedication

Precautions:

Hypertensive crisis; epilepsy; narrow angle glaucoma; symptomatic prostatic hypertrophy; CV disease; hepatic, renal, respiratory impairment; renal failure; stenosing peptic ulcer; bladder neck, pyloroduodenal obstruction; Reye's syndrome (children, adolescents); eczema, rheumatism; high doses; elderly; pregnancy, children

Adverse Reactions:

GI upset, epigastric discomfort; anorexia; sedation, impaired performance, incoordination; dizziness, restlessness; stimulation eg anxiety, hallucinations, incr appetite; dry mouth, blurred vision, urinary hesitancy/ retention, tachycardia; haematological abnormalities incl agranulocytosis; QT prolongation; others, Ask your Phamacist for more details

Interactions:

MAOIs (see Contra); CNS depressants eg alcohol, barbiturates, hypnotics, opioids, anxiolytics, neuroleptics; antimuscarinics eg atropine, TCAs

Dose:

Allergy. Adults: 25-75 mg at night or 10-20 mg 2-3 times daily; children 6-12 yrs: 10-25 mg at night or 10 mg 2-3 times daily; 2-5 yrs: 5-15 mg at night or 5 mg 2-3 times daily. Sedation. Adults: 25-75 mg at night; children 6-12 yrs: 10-25 mg at night; 2-5 yrs: 5-15 mg at night. Travel sickness. Adults: 25 mg; children 6-12 yrs: 10 mg; 2-5 yrs: 5 mg; take night before travel, may repeat 6-8 hrs later. Nausea, vomiting. Adults: 25 mg every 4-6 hrs, max 100 mg/day; children 6-12 yrs: 10 mg every 4-6 hrs, max 25 mg/day; 2-5 yrs: 5 mg every 4-6 hrs, max 15 mg/day