Combined OC. Prevention of pregnancy

Drug Name:

LEVONORGESTREL with ETHINYLOESTRADIOL

Precautions:

Initial, periodic medical history, physical exam; circulatory, cerebrovascular, thromboembolic risk factor(s) (Ask your Phamacist for more details); migraine; jaundice, pruritus, cholestasis; diabetes; hypertriglyceridaemia or family history; gallstones; porphyria; SLE; haemolytic uraemic syndrome; Sydenham's chorea; herpes gestationis; Crohn's disease, ulcerative colitis; otosclerosis; sickle cell disease; chloasma gravidarum history; lactation

Adverse Reactions:

Thromboembolism; migraine; menstrual irregularity; incr hepatic, breast, cervical cancer risk; chloasma; fluid retention; reduced glucose tolerance; depression; hypertension; genitourinary, breast, weight changes; GI upset; headache; hepatic disturbance; rash; contact lens intolerance, cataract; others, Ask your Phamacist for more details

Interactions:

Hepatic enzyme inducers eg hydantoins, barbiturates, primidone, carbamazepine, rifampicin; poss: oxcarbazepine, topiramate, felbamate, ritonavir, griseofulvin, St John's wort; antibiotics eg ampicillin, tetracyclines; cyclosporin; lab tests, Ask your Phamacist for more details

Dose:

Take 1st tab on 1st day of bleeding, from red section marked with appropriate day of wk, then 1 tab/day until pack is empty; commence new pack next day. Changing contraceptive, following pregnancy, abortion, missed tablets, delaying period: Ask your Phamacist for more details

Information provided by MIMS Australia. Copyright © 2008